Paula B Kavathas PhD

Professor of Laboratory Medicine, of Immunobiology and of Molecular, Cellular, and Developmental Biology; Associate Chair for Research; Director, Science Education Outreach Program; Chair, Women's Faculty Forum

Departments & Organizations

Yale Combined Program in the Biological and Biomedical Sciences (BBS): Immunology

Molecular, Cellular, and Developmental BiologyCancer ImmunologyImmunobiology: Science Education Outreach Program; HTILaboratory MedicineImmunology and Immunotherapy

Research Interests

Gene Regulation; Immunology; Molecular Cellular Entities; Receptors; Structure or Function (Health or Safety or Medical); Transgenic Animals more...


  • B.A., University of Wisconsin-Madison, 1972
  • Ph.D., University of Wisconsin-Madison, 1980

Selected Publications

  • The human CD8ß M-4 isoform dominant in effector memory T cells has distinct cytoplasmic motifs that confer unique properties. Thakral D, Coman MM, Bandyopadhyay A, Martin S, Riley JL, Kavathas PB. PLoS One. 2013;8(3):e59374. PMID: 23533620
  • Nod1, but not the ASC inflammasome, contributes to induction of IL-1ß secretion in human trophoblasts after sensing of Chlamydia trachomatis. Kavathas PB, Boeras CM, Mulla MJ, Abrahams VM. Mucosal Immunol. 2013 Mar;6(2):235-43. PMID: 22763410
  • Uric acid induces trophoblast IL-1ß production via the inflammasome: implications for the pathogenesis of preeclampsia. Mulla MJ, Myrtolli K, Potter J, Boeras C, Kavathas PB, Sfakianaki AK, Tadesse S, Norwitz ER, Guller S, Abrahams VM. Am J Reprod Immunol. 2011 Jun;65(6):542-8. PMID: 21352397



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